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It shows 76% (95% in some cases) response with disappearanceof Ph chromosome after 18 months. There isoccasional evening rise of temperature and night sweating.

(1) Bleeding into soft tissue is a complication of abiopsy.

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Emerging genotype-phenotype correlations are guiding genetic counseling. By permissive action is meantthat while they do not themselves produce aneffect, their presence facilitates other hormonesto exert that action, e.g.